Chymoral Forte

drage(Tripsin - Kemotripsin)

1. WHAT IS CHYMORAL Forte AND WHAT IT IS USED FOR
When CHYMORAL FORTE® is administered on an empty stomach as soon as possible after injury occurs, the enteric coated Trypsin and Chymotrypsin are released and absorbed in the small intestine.
This mode of administration protects the enzymes from the destructive activity of the acid pepsin in the stomach and promotes intestinal absorption.
On being absorbed, the enzymes are taken up by the circulating enzyme inhibitors, levels of which show a steep rise following injury and tissue destructive disease. By bringing about an earlier reversal of the rising plasmin inhibitor levels, CHYMORAL FORTE® facilitates the action of plasmin, which is necessary to open up blocked micro circulation, resolve oedema and initiate healing.
Chemoral Forte it is used in :
Resolution of the inflammatory odema, hematoma, pain associated with accidental and surgical trauma, episiotomies, pelvic inflammatory disorders, post-cesarean section, hysterectomy, fractures, muscle and tendon injuries, intervertebral disc hemiation (sciatica) to reduce necrotic damage and to enhance antibiotic penetration in chronic respiratory diseases.

2. WHAT YOU NEED TO KNOW BEFORE YOU START USING CHYMORAL Forte
CHYMORAL Forte is contraindicated in patients with a history of hypersensitivity to enzymes.

Do not take CHYMORAL Forte:
• if you are allergic to enzymes or any of the ingredients listed in this leaflet,

Be particularly careful with CHYMORAL Forte:

CHYMORAL Forte should be used during pregnancy only when clearly needed, as there are no well-controlled studies in pregnant women.
The drug should be administered with caution to patients with a history of hypersensitivity to enzymes.
Taking of the medicine with food or drinks
CHYMORAL Forte should be administered on an empty stomach as soon as possible after injury occurs, the enteric coated Trypsin and Chymotrypsin are released and absorbed in the small intestine.
Pregnancy and breastfeeding
Talk to your doctor or pharmacist before you start taking any medicines.

CHYMORAL Forte should be used during pregnancy only when clearly needed, as there are no well-controlled studies in pregnant women.


Taking other medicines (what you should be aware of if you are using other medicines)

Please inform your doctor or pharmacist if you are taking or if you have previously been taking any other medicines, even those that you buy without a prescription.
Please note that these indications may also refer to the medicines you have been taking in the past or are going to take in the future.
Acids, alkalis and antiseptics (i.e. alcohol) may inactivate chymotrypsin and trypsin. Chloramphenicol inhibits chymotrypsin activity. Epinephrine 1:100 will inactivate chymotrypsin within 1 hour.

3. HOW TO TAKE THE MEDICINE
The oral dose is 1 tablet 4 times a day, half an hour before meals or as directed by Physician. The
tablet must be swallowed whole to preserve the enteric coating. Treatment should begin as soon as possible after injury occurs.
If you take too much of the medicine (overdose)
If you have taken too much of this medicine, immediately consult your doctor or pharmacist.
If you forgot to take a dose:
- Take the missed dose as soon as possible.
- If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose.
- Do not take two doses at the same time.

4. POSSIBLE ADVERSE REACTIONS
Like other medicines, VITAMIN B6 can cause some adverse reactions.
Occasional gastrointestinal irritation, nausea, vomiting and allergic reactions have been reported

5. HOW TO STORE THIS MEDICINE

Store below 25C, protected from light.
Protect from moisture.
KEEP THE MEDICINE OUT OF THE REACH OF CHILDREN!
Shelf-life
36 months

The medicine must not be used beyond the expiry date indicated on the box and on the blister-strip.
Legal category
This medicine is available in pharmacies without medical prescription.

Date of the latest revision of the package leaflet
Package leaflet approved on .......................

Prishtina, September, 2010

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